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Similar content being viewed by others Introduction Non-alcoholic fatty liver disease (NAFLD) is defined as triglyceride accumulation in more than 5% of hepatocytes in the absence of alcohol consumption 1

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Studies that used 1 mg/day in oral and intravenous trials did not show meaningfully better outcomes than lower doses, and higher doses were associated with more reports of headache, diarrhea, and gastrointestinal effects

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Research from the STEP trial program shows that 1.0 mg is where the dose-response curve starts to steepen meaningfully